In a large oven safe skillet (we recommend a cast iron skillet), melt butter over medium heat. Stir in milk, chicken broth, mustard, and salt. Combine well. Add macaroni, stir and heat to a low boil.
Reduce heat to medium low. Simmer for 15 minutes, and cook until pasta is done and sauce thickens. Stir frequently! Add additional milk if needed.
Remove from heat and stir in undrained chiles, black pepper, hot sauce, and 2 cups of the cheese. Stir until melted.
Top with the panko bread crumbs and remaining cheese. Broil a few minutes until cheese on top is melted and bubbly.